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Changelog for TfReg-3.2-1.4.2.i686.rpm :
Thu Jul 13 14:00:00 2017 3.2 New parameters for Cy3/Cy5-DNA. Fixed bug regarding average opening calculation which in certain circumstances would use periodic boundary conditions. Documentation updates.
Tue Apr 11 14:00:00 2017 3.1 New parameter files for group I RNA bulges.
Fri Jan 22 13:00:00 2016 3.0 Fixed important bug concerning matrix multiplications which affects the average opening profiles, especially for symmetric sequences. This may also affect, although very slightly, the melting index and predicted temperatures. Differences in both cases are around 0.01 or less compared to previous versions of tfreg. Fixed bug from version 2.0 which was generating empty files for option -res=prediction with single sequences. Added new base pair representation of type XY^z which introduces context-dependent base pairs. Added optimized parameters for RNA GU. Linking to the library libboost_regex is now required. Code clean up, removed gbc_exp from C++ name space. Adding version identification, see first printed line when running tfreg. You can now add easily your own model potentials. Example scripts were revised for consistency, in particular they no longer accept the data folder as argument. Alternative data folders should be provided by setting the PREFIX command line variable.
Wed Dec 17 13:00:00 2014 2.0 Corrected harmless bug which was causing the last line of a parameter to be read twice. Added a new model -model=mes. Added new option -res=nncheck. Added optimized parameters for deoxyinosine. Files with extension .ver now have an additional column providing RMS(Delta T).
Wed Feb 6 13:00:00 2013 1.1 Improved user documentation. New script tfreg-salt-regression.pl to generate regression files for different salt concentrations. Corrected bug which caused the unnecessary recalculation of quadrature weights, as a result TfReg now runs much faster.
Sat Nov 10 13:00:00 2012 1.0 First Public Release
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