Changelog for TfReg-7.1-1.7.1.x86_64.rpm :

* Thu Sep 01 2022 7.1New parameters DNA with Mg2+ and K+.
* Mon Feb 28 2022 7.0New parameters for metal mediated DNA.
* Wed Apr 07 2021 6.0New LNA and DNA-Mg2+ parameters. Corrections and new example scripts.
* Tue Nov 17 2020 5.3New RNA salt-dependent parameters, new sprediction options. Corrections and new example scripts.
* Mon Jul 13 2020 5.2New parameters for DNA+LNA/DNA and DNA+LNA/RNA. New 3D model.
* Thu Mar 12 2020 5.1New parameters for DNA mismatches.
* Tue Feb 25 2020 5.0New parameters for DNA/TNA hybrids, new features and bug fixes.
* Wed Sep 19 2018 4.0New parameters for DNA/RNA hybrids. Bug fixes. Documentation updates.
* Thu Jul 13 2017 3.2New parameters for Cy3/Cy5-DNA. Fixed bug regarding average opening calculation which in certain circumstances would use periodic boundary conditions. Documentation updates.
* Tue Apr 11 2017 3.1New parameter files for group I RNA bulges.
* Fri Jan 22 2016 3.0Fixed important bug concerning matrix multiplications which affects the average opening profiles, especially for symmetric sequences. This may also affect, although very slightly, the melting index and predicted temperatures. Differences in both cases are around 0.01 or less compared to previous versions of tfreg. Fixed bug from version 2.0 which was generating empty files for option -res=prediction with single sequences. Added new base pair representation of type XY^z which introduces context-dependent base pairs. Added optimized parameters for RNA GU. Linking to the library libboost_regex is now required. Code clean up, removed gbc_exp from C++ name space. Adding version identification, see first printed line when running tfreg. You can now add easily your own model potentials. Example scripts were revised for consistency, in particular they no longer accept the data folder as argument. Alternative data folders should be provided by setting the PREFIX command line variable.
* Wed Dec 17 2014 2.0Corrected harmless bug which was causing the last line of a parameter to be read twice. Added a new model -model=mes. Added new option -res=nncheck. Added optimized parameters for deoxyinosine. Files with extension .ver now have an additional column providing RMS(Delta T).
* Wed Feb 06 2013 1.1Improved user documentation. New script tfreg-salt-regression.pl to generate regression files for different salt concentrations. Corrected bug which caused the unnecessary recalculation of quadrature weights, as a result TfReg now runs much faster.
* Sat Nov 10 2012 1.0First Public Release