| Name : R-CJAMP
| |
| Version : 0.1.1
| Vendor : obs://build_opensuse_org/devel:languages:R
|
| Release : lp155.7.1
| Date : 2024-06-20 11:13:24
|
| Group : Development/Libraries/Other
| Source RPM : R-CJAMP-0.1.1-lp155.7.1.src.rpm
|
| Size : 0.79 MB
| |
| Packager : https://www_suse_com/
| |
| Summary : Copula-Based Joint Analysis of Multiple Phenotypes
|
Description :
We provide a computationally efficient and robust implementation of the
recently proposed C-JAMP (Copula-based Joint Analysis of Multiple
Phenotypes) method (Konigorski et al., 2019, submitted). C-JAMP allows
estimating and testing the association of one or multiple predictors on
multiple outcomes in a joint model, and is implemented here with a
focus on large-scale genome-wide association studies with two
phenotypes. The use of copula functions allows modeling a wide range of
multivariate dependencies between the phenotypes, and previous results
are supporting that C-JAMP can increase the power of association
studies to identify associated genetic variants in comparison to
existing methods (Konigorski, Yilmaz, Pischon, 2016,
< DOI:10.1186/s12919-016-0045-6> Konigorski, Yilmaz, Bull, 2014,
< DOI:10.1186/1753-6561-8-S1-S72>). In addition to the C-JAMP functions,
functions are available to generate genetic and phenotypic data, to
compute the minor allele frequency (MAF) of genetic markers, and to
estimate the phenotypic variance explained by genetic markers.
|
RPM found in directory: /packages/linux-pbone/ftp5.gwdg.de/pub/opensuse/repositories/devel:/languages:/R:/autoCRAN/15.5/x86_64 |
