| Name : R-corto
| |
| Version : 1.2.4
| Vendor : obs://build_opensuse_org/devel:languages:R
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| Release : lp155.4.1
| Date : 2024-06-08 23:23:06
|
| Group : Development/Libraries/Other
| Source RPM : R-corto-1.2.4-lp155.4.1.src.rpm
|
| Size : 3.86 MB
| |
| Packager : https://www_suse_com/
| |
| Summary : Inference of Gene Regulatory Networks
|
Description :
We present \'corto\' (Correlation Tool), a simple package to infer gene
regulatory networks and visualize master regulators from gene
expression data using DPI (Data Processing Inequality) and
bootstrapping to recover edges. An initial step is performed to
calculate all significant edges between a list of source nodes
(centroids) and target genes. Then all triplets containing two
centroids and one target are tested in a DPI step which removes edges.
A bootstrapping process then calculates the robustness of the network,
eventually re-adding edges previously removed by DPI. The algorithm has
been optimized to run outside a computing cluster, using a fast
correlation implementation. The package finally provides functions to
calculate network enrichment analysis from RNA-Seq and ATAC-Seq
signatures as described in the article by Giorgi lab (2020)
< doi:10.1093/bioinformatics/btaa223>.
|
RPM found in directory: /packages/linux-pbone/ftp5.gwdg.de/pub/opensuse/repositories/devel:/languages:/R:/autoCRAN/15.5/x86_64 |
