| Name : R-ActiveDriver
| |
| Version : 1.0.0
| Vendor : obs://build_opensuse_org/devel:languages:R
|
| Release : lp156.2.1
| Date : 2024-06-24 13:52:40
|
| Group : Development/Libraries/Other
| Source RPM : R-ActiveDriver-1.0.0-lp156.2.1.src.rpm
|
| Size : 0.17 MB
| |
| Packager : https://www_suse_com/
| |
| Summary : Finding Cancer Driver Proteins with Enriched Mutations in Post-Translational Modification Sites
|
Description :
A mutation analysis tool that discovers cancer driver genes with
frequent mutations in protein signalling sites such as
post-translational modifications (phosphorylation, ubiquitination,
etc). The Poisson generalised linear regression model identifies genes
where cancer mutations in signalling sites are more frequent than
expected from the sequence of the entire gene. Integration of mutations
with signalling information helps find new driver genes and propose
candidate mechanisms to known drivers. Reference: Systematic analysis
of somatic mutations in phosphorylation signaling predicts novel cancer
drivers. Juri Reimand and Gary D Bader. Molecular Systems Biology
(2013) 9:637 < doi:10.1038/msb.2012.68>.
|
RPM found in directory: /packages/linux-pbone/ftp5.gwdg.de/pub/opensuse/repositories/devel:/languages:/R:/autoCRAN/15.6/x86_64 |
