| Name : R-AssocAFC
| |
| Version : 1.0.2
| Vendor : obs://build_opensuse_org/devel:languages:R
|
| Release : lp153.2.13
| Date : 2024-06-14 11:14:14
|
| Group : Development/Libraries/Other
| Source RPM : R-AssocAFC-1.0.2-lp153.2.13.src.rpm
|
| Size : 0.78 MB
| |
| Packager : (none)
| |
| Summary : Allele Frequency Comparison
|
Description :
When doing association analysis one does not always have the genotypes
for the control population. In such cases it may be necessary to fall
back on frequency based tests using well known sources for the
frequencies in the control population, for instance, from the 1000
Genomes Project. The Allele Frequency Comparison (\'AssocAFC\') package
performs multiple rare variant association analyses in both population
and family-based GWAS (Genome-Wide Association Study) designs. It
includes three score tests that are based on the difference of the sum
of allele frequencies between cases and controls. Two of these tests,
Wcorrected() and Wqls(), are collapsing-based tests and suffer from
having protective and risk variants. The third test, afcSKAT(), is a
score test that overcomes the mix of SNP (Single-Nucleotide
Polymorphism) effect directions. For more details see Saad M and
Wijsman EM (2017) < doi:10.1093/bib/bbx107>.
|
RPM found in directory: /packages/linux-pbone/ftp5.gwdg.de/pub/opensuse/repositories/devel:/languages:/R:/autoCRAN/openSUSE_Leap_15.3/x86_64 |
