| Name : R-Canopy
| |
| Version : 1.3.0
| Vendor : obs://build_opensuse_org/devel:languages:R
|
| Release : lp153.13.5
| Date : 2024-06-14 11:40:12
|
| Group : Development/Libraries/Other
| Source RPM : R-Canopy-1.3.0-lp153.13.5.src.rpm
|
| Size : 0.98 MB
| |
| Packager : (none)
| |
| Summary : Accessing Intra-Tumor Heterogeneity and Tracking Longitudinal and Spatial Clonal Evolutionary History by Next-Generation Sequencing
|
Description :
A statistical framework and computational procedure for identifying the
sub-populations within a tumor, determining the mutation profiles of
each subpopulation, and inferring the tumor\'s phylogenetic history. The
input are variant allele frequencies (VAFs) of somatic single
nucleotide alterations (SNAs) along with allele-specific coverage
ratios between the tumor and matched normal sample for somatic copy
number alterations (CNAs). These quantities can be directly taken from
the output of existing software. Canopy provides a general mathematical
framework for pooling data across samples and sites to infer the
underlying parameters. For SNAs that fall within CNA regions, Canopy
infers their temporal ordering and resolves their phase. When there
are multiple evolutionary configurations consistent with the data,
Canopy outputs all configurations along with their confidence
assessment.
|
RPM found in directory: /packages/linux-pbone/ftp5.gwdg.de/pub/opensuse/repositories/devel:/languages:/R:/autoCRAN/openSUSE_Leap_15.3/x86_64 |
