| Name : R-GEInter
| |
| Version : 0.3.2
| Vendor : obs://build_opensuse_org/devel:languages:R
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| Release : lp153.19.2
| Date : 2024-06-14 12:07:48
|
| Group : Development/Libraries/Other
| Source RPM : R-GEInter-0.3.2-lp153.19.2.src.rpm
|
| Size : 3.02 MB
| |
| Packager : (none)
| |
| Summary : Robust Gene-Environment Interaction Analysis
|
Description :
Description: For the risk, progression, and response to treatment of
many complex diseases, it has been increasingly recognized that
gene-environment interactions play important roles beyond the main
genetic and environmental effects. In practical interaction analyses,
outliers in response variables and covariates are not uncommon. In
addition, missingness in environmental factors is routinely encountered
in epidemiological studies. The developed package consists of five
robust approaches to address the outliers problems, among which two
approaches can also accommodate missingness in environmental factors.
Both continuous and right censored responses are considered. The
proposed approaches are based on penalization and sparse boosting
techniques for identifying important interactions, which are realized
using efficient algorithms. Beyond the gene-environment analysis, the
developed package can also be adopted to conduct analysis on
interactions between other types of low-dimensional and
high-dimensional data. (Mengyun Wu et al (2017),
< doi:10.1080/00949655.2018.1523411> Mengyun Wu et al (2017),
< doi:10.1002/gepi.22055> Yaqing Xu et al (2018),
< doi:10.1080/00949655.2018.1523411> Yaqing Xu et al (2019),
< doi:10.1016/j.ygeno.2018.07.006> Mengyun Wu et al (2021),
< doi:10.1093/bioinformatics/btab318>).
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RPM found in directory: /packages/linux-pbone/ftp5.gwdg.de/pub/opensuse/repositories/devel:/languages:/R:/autoCRAN/openSUSE_Leap_15.3/x86_64 |
