Name : R-GxEprs
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Version : 1.2
| Vendor : obs://build_opensuse_org/devel:languages:R
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Release : lp153.2.2
| Date : 2024-06-14 11:00:19
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Group : Development/Libraries/Other
| Source RPM : R-GxEprs-1.2-lp153.2.2.src.rpm
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Size : 1.32 MB
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Packager : (none)
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Summary : Genotype-by-Environment Interaction in Polygenic Score Models
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Description :
A novel PRS model is introduced to enhance the prediction accuracy by utilising GxE effects. This package performs Genome Wide Association Studies (GWAS) and Genome Wide Environment Interaction Studies (GWEIS) using a discovery dataset. The package has the ability to obtain polygenic risk scores (PRSs) for a target sample. Finally it predicts the risk values of each individual in the target sample. Users have the choice of using existing models (Li et al., 2015) < doi:10.1093/annonc/mdu565>, (Pandis et al., 2013) < doi:10.1093/ejo/cjt054>, (Peyrot et al., 2018) < doi:10.1016/j.biopsych.2017.09.009> and (Song et al., 2022) < doi:10.1038/s41467-022-32407-9>, as well as newly proposed models for genomic risk prediction (refer to the URL for more details).
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RPM found in directory: /packages/linux-pbone/ftp5.gwdg.de/pub/opensuse/repositories/devel:/languages:/R:/autoCRAN/openSUSE_Leap_15.3/x86_64 |