| Name : R-LncPath
| |
| Version : 1.1
| Vendor : obs://build_opensuse_org/devel:languages:R
|
| Release : lp153.7.4
| Date : 2024-06-14 11:40:47
|
| Group : Development/Libraries/Other
| Source RPM : R-LncPath-1.1-lp153.7.4.src.rpm
|
| Size : 2.89 MB
| |
| Packager : (none)
| |
| Summary : Identifying the Pathways Regulated by LncRNA Sets of Interest
|
Description :
Identifies pathways synergisticly regulated by the interested
lncRNA(long non-coding RNA) sets based on a lncRNA-mRNA(messenger RNA)
interaction network. 1) The lncRNA-mRNA interaction network was built
from the protein-protein interactions and the lncRNA-mRNA co-expression
relationships in 28 RNA-Seq data sets. 2) The interested lncRNAs can be
mapped into networks as seed nodes and a random walk strategy will be
performed to evaluate the rate of each coding genes influenced by the
seed lncRNAs. 3) Pathways regulated by the lncRNA set will be evaluated
by a weighted Kolmogorov-Smirnov statistic as an ES Score. 4) The p
value and false discovery rate value will also be calculated through a
permutation analysis. 5) The running score of each pathway can be
plotted and the heat map of each pathway can also be plotted if an
expression profile is provided. 6) The rank and scores of the gene list
of each pathway can be printed.
|
RPM found in directory: /packages/linux-pbone/ftp5.gwdg.de/pub/opensuse/repositories/devel:/languages:/R:/autoCRAN/openSUSE_Leap_15.3/x86_64 |
