| Name : R-MetaSubtract
| |
| Version : 1.60
| Vendor : obs://build_opensuse_org/devel:languages:R
|
| Release : lp153.2.13
| Date : 2024-06-14 11:03:11
|
| Group : Development/Libraries/Other
| Source RPM : R-MetaSubtract-1.60-lp153.2.13.src.rpm
|
| Size : 0.38 MB
| |
| Packager : (none)
| |
| Summary : Subtracting Summary Statistics of One or more Cohorts from Meta-GWAS Results
|
Description :
If results from a meta-GWAS are used for validation in one of the
cohorts that was included in the meta-analysis, this will yield biased
(i.e. too optimistic) results. The validation cohort needs to be
independent from the meta-Genome-Wide-Association-Study (meta-GWAS)
results. \'MetaSubtract\' will subtract the results of the respective
cohort from the meta-GWAS results analytically without having to redo
the meta-GWAS analysis using the leave-one-out methodology. It can
handle different meta-analyses methods and takes into account if single
or double genomic control correction was applied to the original
meta-analysis. It can also handle different meta-analysis methods. It
can be used for whole GWAS, but also for a limited set of genetic
markers. See for application: Nolte I.M. et al. (2017); < doi:
10.1038/ejhg.2017.50>.
|
RPM found in directory: /packages/linux-pbone/ftp5.gwdg.de/pub/opensuse/repositories/devel:/languages:/R:/autoCRAN/openSUSE_Leap_15.3/x86_64 |
