| Name : R-PriorCD
| |
| Version : 0.1.0
| Vendor : obs://build_opensuse_org/devel:languages:R
|
| Release : lp153.4.11
| Date : 2024-06-14 12:04:11
|
| Group : Development/Libraries/Other
| Source RPM : R-PriorCD-0.1.0-lp153.4.11.src.rpm
|
| Size : 1.55 MB
| |
| Packager : (none)
| |
| Summary : Prioritizing Cancer Drugs for Interested Cancer
|
Description :
Prioritize candidate cancer drugs for drug repositioning based on the
random walk with restart algorithm in a drug-drug functional similarity
network. 1) We firstly constructed a drug-drug functional similarity
network by integrating pathway activity and drug activity derived from
the NCI-60 cancer cell lines. 2) Secondly, we calculated drug
repurposing score according to a set of approved therapeutic drugs of
interested cancer based on the random walk with restart algorithm in
the drug-drug functional similarity network. 3) Finally, the
permutation test was used to calculate the statistical significance
level for the drug repurposing score.
|
RPM found in directory: /packages/linux-pbone/ftp5.gwdg.de/pub/opensuse/repositories/devel:/languages:/R:/autoCRAN/openSUSE_Leap_15.3/x86_64 |
