| Name : R-RZooRoH
| |
| Version : 0.3.2.1
| Vendor : obs://build_opensuse_org/devel:languages:R
|
| Release : lp153.1.4
| Date : 2024-06-14 11:34:17
|
| Group : Development/Libraries/Other
| Source RPM : R-RZooRoH-0.3.2.1-lp153.1.4.src.rpm
|
| Size : 4.15 MB
| |
| Packager : (none)
| |
| Summary : Partitioning of Individual Autozygosity into Multiple Homozygous-by-Descent Classes
|
Description :
Functions to identify Homozygous-by-Descent (HBD) segments associated
with runs of homozygosity (ROH) and to estimate individual autozygosity
(or inbreeding coefficient). HBD segments and autozygosity are assigned
to multiple HBD classes with a model-based approach relying on a
mixture of exponential distributions. The rate of the exponential
distribution is distinct for each HBD class and defines the expected
length of the HBD segments. These HBD classes are therefore related to
the age of the segments (longer segments and smaller rates for recent
autozygosity / recent common ancestor). The functions allow to estimate
the parameters of the model (rates of the exponential distributions,
mixing proportions), to estimate global and local autozygosity
probabilities and to identify HBD segments with the Viterbi decoding.
The method is fully described in Druet and Gautier (2017)
< doi:10.1111/mec.14324>.
|
RPM found in directory: /packages/linux-pbone/ftp5.gwdg.de/pub/opensuse/repositories/devel:/languages:/R:/autoCRAN/openSUSE_Leap_15.3/x86_64 |
