| Name : R-ToxCrit
| |
| Version : 1.0
| Vendor : obs://build_opensuse_org/devel:languages:R
|
| Release : lp153.1.12
| Date : 2024-06-14 11:04:26
|
| Group : Development/Libraries/Other
| Source RPM : R-ToxCrit-1.0-lp153.1.12.src.rpm
|
| Size : 0.01 MB
| |
| Packager : (none)
| |
| Summary : Calculates Safety Stopping Boundaries for a Single-Arm Trial using Bayes
|
Description :
Computation of stopping boundaries for a single-arm trial using a
Bayesian criterion; i.e., for each m< =n (n= total patient number of the
trial) the smallest number of observed toxicities is calculated leading
to the termination of the trial/accrual according to the specified
criteria. The probabilities of stopping the trial/accrual at and up
until (resp.) the m-th patient (m< =n) is also calculated. This design
is more conservative than the frequentist approach (using Clopper
Pearson CIs) which might be preferred as it concerns safety.See also
Aamot et.al.(2010) \"Continuous monitoring of toxicity in clinical
trials - simulating the risk of stopping prematurely\"
< doi:10.5414/cpp48476>.
|
RPM found in directory: /packages/linux-pbone/ftp5.gwdg.de/pub/opensuse/repositories/devel:/languages:/R:/autoCRAN/openSUSE_Leap_15.3/x86_64 |
