| Name : R-cwot
| |
| Version : 0.1.0
| Vendor : obs://build_opensuse_org/devel:languages:R
|
| Release : lp153.1.8
| Date : 2024-06-14 11:18:18
|
| Group : Development/Libraries/Other
| Source RPM : R-cwot-0.1.0-lp153.1.8.src.rpm
|
| Size : 0.03 MB
| |
| Packager : (none)
| |
| Summary : Cauchy Weighted Joint Test for Pharmacogenetics Analysis
|
Description :
A flexible and robust joint test of the single nucleotide polymorphism
(SNP) main effect and genotype-by-treatment interaction effect for
continuous and binary endpoints. Two analytic procedures, Cauchy
weighted joint test (CWOT) and adaptively weighted joint test (AWOT),
are proposed to accurately calculate the joint test p-value. The
proposed methods are evaluated through extensive simulations under
various scenarios. The results show that the proposed AWOT and CWOT
control type I error well and outperform existing methods in detecting
the most interesting signal patterns in pharmacogenetics (PGx)
association studies. For reference, see Hong Zhang, Devan Mehrotra and
Judong Shen (2022) < doi:10.13140/RG.2.2.28323.53280>.
|
RPM found in directory: /packages/linux-pbone/ftp5.gwdg.de/pub/opensuse/repositories/devel:/languages:/R:/autoCRAN/openSUSE_Leap_15.3/x86_64 |
