| Name : R-drugCombo
| |
| Version : 1.2.1
| Vendor : obs://build_opensuse_org/devel:languages:R
|
| Release : lp153.3.12
| Date : 2024-06-14 12:08:41
|
| Group : Development/Libraries/Other
| Source RPM : R-drugCombo-1.2.1-lp153.3.12.src.rpm
|
| Size : 2.39 MB
| |
| Packager : (none)
| |
| Summary : Drug Interaction Modeling Based on Loewe Additivity Following Harbron\'s Approach
|
Description :
Perform assessment of synergy/antagonism for drug combinations based on
the Loewe additivity model, following Harbron\'s approach (Statistics in
Medicine, 2010, < doi:10.1002/sim.3916>). The package allows flexible
modeling of the drug interaction index and supports \"2-stage\"
estimation in addition to \"1-stage\" estimation, including
bootstrap-based confidence intervals. The method requires data on the
monotherapy responses and the package accommodates both checkerboard
and ray designs. Functions are available for graphical exploration of
model goodness-of-fit and diagnostics, as well as for
synergy/antagonism assessment in 2D and 3D.
|
RPM found in directory: /packages/linux-pbone/ftp5.gwdg.de/pub/opensuse/repositories/devel:/languages:/R:/autoCRAN/openSUSE_Leap_15.3/x86_64 |
