| Name : R-emba
| |
| Version : 0.1.8
| Vendor : obs://build_opensuse_org/devel:languages:R
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| Release : lp153.14.5
| Date : 2024-06-14 12:04:14
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| Group : Development/Libraries/Other
| Source RPM : R-emba-0.1.8-lp153.14.5.src.rpm
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| Size : 1.99 MB
| |
| Packager : (none)
| |
| Summary : Ensemble Boolean Model Biomarker Analysis
|
Description :
Analysis and visualization of an ensemble of boolean models for
biomarker discovery in cancer cell networks. The package allows to
easily load the simulation data results of the DrugLogics software
pipeline which predicts synergistic drug combinations in cancer cell
lines (developed by the DrugLogics research group in NTNU). It has
generic functions that can be used to split a boolean model dataset to
model groups with regards to the models predictive performance (number
of true positive predictions/Matthews correlation coefficient score) or
synergy prediction based on a given set of gold standard synergies and
find the average activity difference per network node between all model
group pairs. Thus, given user-specific thresholds, important nodes
(biomarkers) can be accessed in the sense that they make the models
predict specific synergies (synergy biomarkers) or have better
performance in general (performance biomarkers). Lastly, if the boolean
models have a specific equation form and differ only in their link
operator, link operator biomarkers can also be found.
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RPM found in directory: /packages/linux-pbone/ftp5.gwdg.de/pub/opensuse/repositories/devel:/languages:/R:/autoCRAN/openSUSE_Leap_15.3/x86_64 |
