| Name : R-hscovar
| |
| Version : 0.4.2
| Vendor : obs://build_opensuse_org/devel:languages:R
|
| Release : lp153.1.12
| Date : 2024-06-14 11:27:03
|
| Group : Development/Libraries/Other
| Source RPM : R-hscovar-0.4.2-lp153.1.12.src.rpm
|
| Size : 0.30 MB
| |
| Packager : (none)
| |
| Summary : Calculation of Covariance Between Markers for Half-Sib Families
|
Description :
The theoretical covariance between pairs of markers is calculated from
either paternal haplotypes and maternal linkage disequilibrium (LD) or
vise versa. A genetic map is required. Grouping of markers is based on
the correlation matrix and a representative marker is suggested for
each group. Employing the correlation matrix, optimal sample size can
be derived for association studies based on a SNP-BLUP approach. The
implementation relies on paternal half-sib families and biallelic
markers. If maternal half-sib families are used, the roles of sire/dam
are swapped. Multiple families can be considered. Wittenburg, Bonk,
Doschoris, Reyer (2020) \"Design of Experiments for Fine-Mapping
Quantitative Trait Loci in Livestock Populations\"
< doi:10.1186/s12863-020-00871-1>. Carlson, Eberle, Rieder, Yi,
Kruglyak, Nickerson (2004) \"Selecting a maximally informative set of
single-nucleotide polymorphisms for association analyses using linkage
disequilibrium\" < doi:10.1086/381000>.
|
RPM found in directory: /packages/linux-pbone/ftp5.gwdg.de/pub/opensuse/repositories/devel:/languages:/R:/autoCRAN/openSUSE_Leap_15.3/x86_64 |
