| Name : R-sigora
| |
| Version : 3.1.1
| Vendor : obs://build_opensuse_org/devel:languages:R
|
| Release : lp153.1.11
| Date : 2024-06-14 11:23:02
|
| Group : Development/Libraries/Other
| Source RPM : R-sigora-3.1.1-lp153.1.11.src.rpm
|
| Size : 3.24 MB
| |
| Packager : (none)
| |
| Summary : Signature Overrepresentation Analysis
|
Description :
Pathway Analysis is statistically linking observations on the molecular
level to biological processes or pathways on the systems(i.e.,
organism, organ, tissue, cell) level. Traditionally, pathway analysis
methods regard pathways as collections of single genes and treat all
genes in a pathway as equally informative. However, this can lead to
identifying spurious pathways as statistically significant since
components are often shared amongst pathways. SIGORA seeks to avoid
this pitfall by focusing on genes or gene pairs that are (as a
combination) specific to a single pathway. In relying on such pathway
gene-pair signatures (Pathway-GPS), SIGORA inherently uses the status
of other genes in the experimental context to identify the most
relevant pathways. The current version allows for pathway analysis of
human and mouse datasets. In addition, it contains pre-computed
Pathway-GPS data for pathways in the KEGG and Reactome pathway
repositories and mechanisms for extracting GPS for user-supplied
repositories.
|
RPM found in directory: /packages/linux-pbone/ftp5.gwdg.de/pub/opensuse/repositories/devel:/languages:/R:/autoCRAN/openSUSE_Leap_15.3/x86_64 |
