| Name : R-bakR
| |
| Version : 1.0.1
| Vendor : obs://build_opensuse_org/devel:languages:R
|
| Release : lp155.2.1
| Date : 2024-09-18 13:07:30
|
| Group : Development/Libraries/Other
| Source RPM : R-bakR-1.0.1-lp155.2.1.src.rpm
|
| Size : 6.84 MB
| |
| Packager : https://www_suse_com/
| |
| Summary : Analyze and Compare Nucleotide Recoding RNA Sequencing Datasets
|
Description :
Several implementations of a novel Bayesian hierarchical statistical
model of nucleotide recoding RNA-seq experiments (NR-seq;
TimeLapse-seq, SLAM-seq, TUC-seq, etc.) for analyzing and comparing
NR-seq datasets (see \'Vock and Simon\' (2023)
< doi:10.1261/rna.079451.122>). NR-seq is a powerful extension of
RNA-seq that provides information about the kinetics of RNA metabolism
(e.g., RNA degradation rate constants), which is notably lacking in
standard RNA-seq data. The statistical model makes maximal use of these
high-throughput datasets by sharing information across transcripts to
significantly improve uncertainty quantification and increase
statistical power. \'bakR\' includes a maximally efficient implementation
of this model for conservative initial investigations of datasets.
\'bakR\' also provides more highly powered implementations using the
probabilistic programming language \'Stan\' to sample from the full
posterior distribution. \'bakR\' performs multiple-test adjusted
statistical inference with the output of these model implementations to
help biologists separate signal from background. Methods to
automatically visualize key results and detect batch effects are also
provided.
|
RPM found in directory: /packages/linux-pbone/ftp5.gwdg.de/pub/opensuse/repositories/devel:/languages:/R:/autoCRAN/15.5/x86_64 |
